Year : 2017  |  Volume : 11  |  Issue : 2  |  Page : 161-164

Primary pulmonary extraskeletal Ewing sarcoma/Primitive neuroectodermal tumor: Two case reports

1 Department of Chest Diseases, Al-Zahraa University Hospital, Cairo, Egypt
2 Department of Clinical Oncology, Al Hussein University Hospital, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
3 Department of Pathology, Cairo University, Cairo, Egypt

Correspondence Address:
Eman Sobh
Department of Chest, Al-Zahraa University Hospital, Faculty of Medicine, Al-Azhar University, Al-Abbassia - 11517, Cairo
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ejb.ejb_48_16

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Primary pulmonary extraskeletal Ewing sarcoma (EES)/primitive neuroectodermal tumor is an extremely rare tumor with only few cases reported in the literature. In this study, we present two cases of primary pulmonary EES diagnosed and treated at our institution. The median age was 20 years (range: 19–21). Cough, dyspnea, and hemoptysis were the predominant features at presentation, associated with a large lung mass on imaging. Image-guided core needle biopsies were the diagnostic modalities for both patients. Initial histopathology showed malignant small round cell tumor, which has been confirmed by immunohistochemistry as EES. Both patients received neoadjuvant chemotherapy followed by surgery; postoperative pathology for the first patient showed 98% tumor necrosis, whereas the second patient’s pathology showed no evidence of residual tumor after complete surgical excision.

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